Aminobenzoic acids and derivatives
Medchemexpress LLC Schisantherin A | 58546-56-8 | 151529 | 536.57 | 1 ML
Schisantherin A, also known as Gomisin-C, is a dibenzocyclooctadiene lignan. It inhibits p65-NF-κB translocation into the nucleus by IκBα degradation and has varied beneficial pharmacological effects, including anti-inflammatory properties and protection against acute respiratory distress syndrome.
- Inhibits p65-NF-κB translocation into the nucleus
- Decreases concentrations of TNF-α and IL-6
- Reduces nitric oxide (NO) and prostaglandin E2 (PGE2) production
- Exhibits anti-inflammatory properties by down-regulating NF-κB and MAPK signaling pathways
- Protects against lipopolysaccharide-induced acute respiratory distress syndrome in mice
- Shows antiproliferative activity against various human cancer cell lines
Chemscene 5-(Trimethylsilyl)pent-4-yn-1-ol | 10g | CS-W016228 | 96% | 13224-84-5 | MFCD00190229 | 156 30 | C8H16OSi
Chemscene | 5-(Trimethylsilyl)pent-4-yn-1-ol | 10g | CS-W016228 | 96% | 13224-84-5 | MFCD00190229 | 156 30 | C8H16OSi
Medchemexpress LLC 2-tert-butyl-1,4-benzoquinone | 3602-55-9 | MFCD00666928 | 99.0% | 164.20 g/mol | C10H12O2 | 10 G
2-tert-butyl-1,4-benzoquinone is a tert-butyl substituted 1,4-benzoquinone supplied for laboratory research. It is reported as an electrophilic metabolite of butylated hydroxyanisole and as an oxidation product of 2-tert-butylhydroquinone. The material is provided as a light yellow solid and is characterized by a molecular formula of C10H12O2, a molecular weight of 164.20 g/mol, and manufacturer-reported GC purity of 99%.
- Light yellow solid appearance.
- Molecular formula C10H12O2 and molecular weight 164.20 g/mol.
- High purity: 99.0% (GC) per certificate of analysis.
- Analytical data includes GC purity, water (KF), residue on ignition, and 1H NMR confirmation.
- Storage recommendations provided for powder and for solutions to maintain stability.
- Available in multiple laboratory-scale package sizes.
Chemscene Sodium 2-oxopropanoate | 1kg | CS-W016629 | 98% | 113-24-6 | MFCD00002586 | 110 04 | C3H3NaO3
Chemscene | Sodium 2-oxopropanoate | 1kg | CS-W016629 | 98% | 113-24-6 | MFCD00002586 | 110 04 | C3H3NaO3
Chemscene 2-Cyclopropyl-4 4 5 5-tetramethyl-1 3 2-dioxaborolane | 5g | CS-W007591 | 98% | 126689-01-8 | MFCD05663847 | 168 04 | C9H17BO2
Chemscene | 2-Cyclopropyl-4 4 5 5-tetramethyl-1 3 2-dioxaborolane | 5g | CS-W007591 | 98% | 126689-01-8 | MFCD05663847 | 168 04 | C9H17BO2
eMolecules 1423-26-3 | 3-(Trifluoromethyl)phenylboronic Acid | Accela ChemBio (ASD) | MFCD00151854 | 189.930 | C7H6BF3O2 | 98.000 | OB(O)c1cccc(c1)C(F)(F)F | 25g | 452412294
3-(Trifluoromethyl)phenylboronic Acid | Accela ChemBio (ASD) | 1423-26-3 | MFCD00151854 | 189.930 | C7H6BF3O2 | 98.000 | OB(O)c1cccc(c1)C(F)(F)F | 25g | 452412294
Medchemexpress LLC PI3-Kinase p110 β Antibody (YA5808) | Predicted band size: 123 kDa; Observed band size: 110 kDa | 50 UL
PI3-Kinase p110 β is a phosphoinositide-3-kinase (PI3K) pivotal for cell signaling. It phosphorylates phosphatidylinositol derivatives, producing PIP3, which activates cascades vital for cell growth, survival, proliferation, and motility. This kinase is involved in AKT1 activation, platelet function, autophagy, insulin signaling, and mediates oncogenic signals.
- Rabbit-derived, non-conjugated IgG monoclonal antibody
- Reacts with human, mouse, and rat samples
- Purified by protein A
- Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Suitable for IHC-P, WB, ICC/IF, ELISA, and IP applications
- Plays crucial roles in cell growth, survival, proliferation, and motility signaling
- Involved in AKT1 activation and platelet function
- Impacts autophagy, insulin signaling, and clathrin-mediated endocytosis
Chemscene Pramipexole | 1g | CS-2510 | 98% | 104632-26-0 | MFCD00869076 | 211 33 | C10H17N3S
Chemscene | Pramipexole | 1g | CS-2510 | 98% | 104632-26-0 | MFCD00869076 | 211 33 | C10H17N3S
Medchemexpress LLC Ac-Exatecan | 2922852-48-8 | 99.0% | C26H24FN3O5 | 50 MG
Ac-Exatecan is an acetylation-modified Exatecan, which acts as a common toxin component in Antibody-Drug Conjugate (ADC) preparation and is an inhibitor of DNA topoisomerase I (IC50 = 2.2 μM). This compound demonstrates antitumor activity and can serve as a payload for ADCs. Furthermore, Exatecan is effective against P-glycoprotein-mediated multi-drug resistant cells. This product is for research use only.
- Acetylation-modified Exatecan
- Common toxin component in antibody-drug conjugate (ADC) preparation
- Inhibitor of DNA topoisomerase I (IC50 = 2.2 μM)
- Demonstrates antitumor activity
- Can serve as a payload for ADCs
- Effective against P-glycoprotein-mediated multi-drug resistant cells
Medchemexpress LLC 4-Acetamidophenyl acetate | 2623-33-8 | >=97.0% | C10H11NO3 | 1 ML
4-Acetamidophenyl acetate is an impurity of Acetaminophen and acts as an intermediate in its synthesis. It is classified as harmful if swallowed, causes skin irritation, causes serious eye irritation, and may cause respiratory irritation.
- Selective COX-2 inhibitor (IC50=25.8 μM)
- Potent hepatic N-acetyltransferase 2 (NAT2) inhibitor
- Undergoes hydrolytic cleavage independent of microsomes and cofactors in rat liver microsomal metabolism assays in vitro
- Harmful if swallowed
- Causes skin irritation
- Causes serious eye irritation
- May cause respiratory irritation
Medchemexpress LLC 9-Fluorenylmethanol | 24324-17-2 | 99.0% | 196.25 | 500 G
9-Fluorenylmethanol is an N-protecting reagent primarily used in peptide synthesis. This product is suitable for laboratory centrifugation and storage.
- N-protecting reagent
- Used in peptide synthesis
- Solid appearance
- Off-white to light yellow color
Chemscene N1 N1-dibutylpropane-1 3-diamine | 100g | CS-W016886 | 98% | 102-83-0 | MFCD00008219 | 186 34 | C11H26N2
Chemscene | N1 N1-dibutylpropane-1 3-diamine | 100g | CS-W016886 | 98% | 102-83-0 | MFCD00008219 | 186 34 | C11H26N2
Chemscene MorDalphos | 250mg | CS-W011550 | 97% | 1237588-12-3 | MFCD17018759 | 463 63 | C30H42NOP
Chemscene | MorDalphos | 250mg | CS-W011550 | 97% | 1237588-12-3 | MFCD17018759 | 463 63 | C30H42NOP
Chemscene 2 2 -Disulfanediyldibenzoic acid | 1kg | CS-W012089 | 95% | 119-80-2 | MFCD00002465 | 306 36 | C14H10O4S2
Chemscene | 2 2 -Disulfanediyldibenzoic acid | 1kg | CS-W012089 | 95% | 119-80-2 | MFCD00002465 | 306 36 | C14H10O4S2
Medchemexpress LLC p-Hydroxymandelic acid | 1198-84-1 | 95.5% | 168.15 | 500 MG
p-Hydroxymandelic acid is a valuable aromatic fine chemical and widely used for production of pharmaceuticals and food additives. It is also used in the production of aromatic drugs and flavors, and for the preparation of 4-hydroxyphenylacetic acid, a synthetic precursor of the selective β1-receptor antagonist drug atenolol. Additionally, p-Hydroxymandelic acid can conjugate cytotoxic drugs and enzyme substrates, suggesting its application in targeted drug delivery systems.
- Valuable aromatic fine chemical.
- Used for production of pharmaceuticals.
- Used for production of food additives.
- Applied in targeted drug delivery systems.